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Dysregulation of Amyloid Precursor Protein impairs adipose tissue mitochondrial function and promotes obesity

ABSTRACT: Mitochondria from subcutaneous white adipose tissues of control or signal recognition particle 54c (SPR54c) transgenic mice were isolated and underwent further Percoll gradient-based purification. Purified mitochondria were subject to mass-spectrometry based proteomic analysis performed by UT Southwestern Proteomics Core. ID# 696496: SRP54c Transgenic; ID# 696497: control.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

SUBMITTER: Philipp Scherer

PROVIDER: MSV000084498 | MassIVE | Thu Oct 24 08:57:00 BST 2019

REPOSITORIES: MassIVE

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