Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Plasma Protein Signatures in Alcoholic Hepatitis

ABSTRACT: Supporting plasma proteomic data from clinical patients with alcoholic hepatitis in comparison to relevant controls and across treatment time points, baseline, 28/29 days, 12 weeks. Samples were digested with trypsin, labeled with TMT 10-Plex, then analyzed by LC-MS/MS. Data was searched with MS-GF+ using PNNL's DMS Processing pipeline.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Jon M. Jacobs

PROVIDER: MSV000084528 | MassIVE | Fri Nov 01 19:19:00 GMT 2019

SECONDARY ACCESSION(S): PXD016117

REPOSITORIES: MassIVE

ACCESS DATA

Json Xml

Similar Datasets

Pathogenesis of alcoholic hepatitis

Project description:Pathogenesis of alcoholic hepatitis

| PRJNA704267 | ENA

Hepatic cell proliferation and outcome in alcoholic hepatitis: histology, gene expression and effect of stem cell therapy

Project description:Regeneration and alcoholic hepatitis

2014-08-31 | E-MTAB-2664 | biostudies-arrayexpress

Silent Alcoholic Steatohepatitis vs Alcoholic Hepatitis: Clinical, Histological and Transcriptome Analysis

Project description:Silent Alcoholic Steatohepatitis vs Alcoholic Hepatitis: Clinical, Histological and Transcriptome Analysis

| PRJNA635585 | ENA

INTEAM CONSORTIUM - ALCOHOLIC HEPATITIS LIVER RNA SEQUENCING

Project description:INTEAM CONSORTIUM - ALCOHOLIC HEPATITIS LIVER RNA SEQUENCING

| PRJNA531222 | ENA

INTEAM CONSORTIUM - ALCOHOLIC HEPATITIS LIVER RNA SEQUENCING

Project description:INTEAM CONSORTIUM - ALCOHOLIC HEPATITIS LIVER RNA SEQUENCING

| PRJNA531223 | ENA

Super Enhancer Regulation of Cytokine-Induced Chemokine Production in Alcoholic Hepatitis [RNA-Seq]

Project description:Super enhancer in liver propagates inflammatory signaling by super enhancer-mediatedinducing chemokine expression and is the therapeutic potential of BET inhibition in Alcoholic hepatitis(AH) treatment.

2020-10-19 | GSE155907 | GEO

Hepatic protein and phosphoprotein signatures of alcohol-associated cirrhosis and hepatitis

Project description:LC-MS/MS tryptic peptide data comprising TMT10 analysis of both global and phosphoproteome of alcoholic hepatitis liver with relevant controls. Two sets of data include both explant liver samples and liver biopsy data. Data was searched with MS-GF+.

2022-03-30 | MSV000089168 | MassIVE

Transcriptome profiles of liver biopsy tissues from sever alcoholic hepatitis patients (derivation cohort)

Project description:Corticosteroids are the current standard of care to improve short-term mortality in severe alcoholic hepatitis (AH), although nearly 40% of the patients do not respond and accurate pre-treatment predictors are lacking. We developed 123-gene prognostic score based on molecular and clinical variables before initiation of corticosteroids. Furthermore, The gene signature was implemented in an FDA-approved platform (NanoString), and verified for technical validity and prognostic capability. Here we demonstrated that a Nanostring-based gene expressoin risk classificatoin is useful to predict mortality in patients with severe alcoholic hepatitis who were treated by corticosteroid

2018-02-18 | GSE94397 | GEO

Transcriptome profiles of liver biopsy tissues from sever alcoholic hepatitis patients (validation cohort, Brussels)

Project description:Corticosteroids are the current standard of care to improve short_term mortality in severe alcoholic hepatitis (AH), although nearly 40% of the patients do not respond and accurate pre_treatment predictors are lacking. We developed 123_gene prognostic score based on molecular and clinical variables before initiation of corticosteroids. Furthermore, The gene signature was implemented in an FDA_approved platform (NanoString), and verified for technical validity and prognostic capability. Here we demonstrated that a Nanostring_based gene expressoin risk classificatoin is useful to predict mortality in patients with severe alcoholic hepatitis who were treated by corticosteroid

2018-02-18 | GSE94399 | GEO

Super Enhancer Regulation of Cytokine-Induced Chemokine Production in Alcoholic Hepatitis [ChIP-Seq 2]

2021-02-28 | GSE166005 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data