S-nitrosylation in zebra fish tissue regeneration

ABSTRACT: we found that inducible nitric oxide synthase (iNOS) is critical to this process by virtue of its ability to induce post-translational S-nitrosylation of epigenetic enzymes. The possible link between induction of PSC, S-nitrosylation and tissue regeneration remains largely unexplored. Here, we show that the inducible NO synthase (iNOS) translocates from the cytoplasm to the nucleus during regeneration of the zebrafish tailfin and that this is associated with alterations in the nuclear S-nitrosylome.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Danio Rerio (ncbitaxon:7955)

SUBMITTER: Gianfranco Matrone  

PROVIDER: MSV000085055 | MassIVE | Wed Mar 04 14:07:00 GMT 2020

SECONDARY ACCESSION(S): PXD017883

REPOSITORIES: MassIVE