Small molecule inhibitor of NEDD4

ABSTRACT: WT and A53T alpha-synculein-expressing SH-SY5Y cells were treated with sham (DMSO), NAB2 or NAB17 followed by enrichment with TUBE agarose. Eluents were reduced and alkylated and digested with trypsin using an S-trap. Lyophilized peptides were analyzed by LC-MS/MS followed by label-free quantification as described in the attached methods.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Dewey G. McCafferty  

PROVIDER: MSV000085432 | MassIVE | Sun May 17 19:19:00 BST 2020

SECONDARY ACCESSION(S): PXD019245

REPOSITORIES: MassIVE