Proteomics

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Shotgun proteomics of Vero E6 cells infected by Italy-INMI1 SARS-CoV-2 virus

ABSTRACT: Next-generation proteomics of Vero E6 cells infected by Italy-INMI1 SARS-CoV-2 virus for defining the kinetics of whole viral particle antigen production for vaccines. Cells from Day1, Day2, Day3, Day4, Day7 post-infection at two multiplicities of infection.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Betacoronavirus Sp. (ncbitaxon:1928434) Chlorocebus Aethiops Aethiops (ncbitaxon:101841)

SUBMITTER: Jean Armengaud  

PROVIDER: MSV000085510 | MassIVE | Fri May 29 16:50:00 BST 2020

SECONDARY ACCESSION(S): PXD018594

REPOSITORIES: MassIVE

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Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has resulted in a pandemic and is continuing to spread rapidly around the globe. No effective vaccine is currently available to prevent COVID-19, and intense efforts are being invested worldwide into vaccine development. In this context, all technology platforms must overcome several challenges resulting from the use of an incompletely characterized new virus. These include finding the right conditions for virus amplification f  ...[more]

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