Quantitative Proteomics of the Cancer Cell Line Encyclopedia

ABSTRACT: The Cancer Cell Line Encyclopedia (CCLE) is a collaborative effort to generate steady-state large-scale profiling across a collection of nearly a thousand cancer cell lines. Multiple generations of this effort have resulted in a collection of many data types such as RNA expression, mutation annotation, and drug sensitivity data. Included here are whole proteome profiles for 375 cell lines in this collection collected using TMT 10-plex reagent and SPS-MS3 acquisition. They include cell lines from many tissue lineages with various underlying oncogenic mutations. The fully normalized data downstream of these raw files as well as the many other datasets in the CCLE are availble at https://depmap.org/portal/.

INSTRUMENT(S): Orbitrap Fusion Lumos, Orbitrap Fusion

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Steven P Gygi  

PROVIDER: MSV000085836 | MassIVE | Mon Jul 27 18:01:00 BST 2020

REPOSITORIES: MassIVE