Proteomics

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Proteomics of the developing human lung

ABSTRACT: Proteomic data from human lung collected from human donors spanning 10 timepoints between 1 day old and 8 years old. Samples were digested with trypsin, then analyzed by LC-MS/MS. Data was searched with MS-GF+ using PNNL's DMS processing pipeline.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Charles Ansong  

PROVIDER: MSV000085929 | MassIVE | Fri Aug 07 16:37:00 BST 2020

SECONDARY ACCESSION(S): PXD020798

REPOSITORIES: MassIVE

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<b>Rationale:</b> The current understanding of human lung development derives mostly from animal studies. Although transcript-level studies have analyzed human donor tissue to identify genes expressed during normal human lung development, protein-level analysis that would enable the generation of new hypotheses on the processes involved in pulmonary development are lacking. <b>Objectives:</b> To define the temporal dynamic of protein expression during human lung development. <b>Methods:</b> We p  ...[more]

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