Large bidirectional remodeling of the Myc-induced cell surface proteome in B-cells and prostate cells creates new opportunities for immunotherapy

ABSTRACT: To identify how MYC overexpression remodels the cell surface proteome in a cell autologous fashion and in different cell types, we investigated the impact of MYC overexpression on ~800 surface proteins in three isogenic model cell lines either of B-cell or prostate cell origin that were engineered to contain either high or low MYC.

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: James Wells  

PROVIDER: MSV000085930 | MassIVE | Fri Aug 07 19:40:00 BST 2020

SECONDARY ACCESSION(S): PXD020799

REPOSITORIES: MassIVE