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Identification of TULP3 protein interactions

ABSTRACT: Table S1: Anti-FLAG immunoprecipitation on HEK293T cell lysates stably expressing FLAG-TULP3 .

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Olivier Julien Basil Hubbard

PROVIDER: MSV000086357 | MassIVE | Thu Oct 22 10:22:00 BST 2020

REPOSITORIES: MassIVE

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Publications

A conserved acetylation switch enables pharmacological control of tubby-like protein stability.

Kerek Evan M EM Yoon Kevin H KH Luo Shu Y SY Chen Jerry J Valencia Robert R Julien Olivier O Waskiewicz Andrew J AJ Hubbard Basil P BP

The Journal of biological chemistry 20201123

Tubby-like proteins (TULPs) are characterized by a conserved C-terminal domain that binds phosphoinositides. Collectively, mammalian TULP1-4 proteins play essential roles in intracellular transport, cell differentiation, signaling, and motility. Yet, little is known about how the function of these proteins is regulated in cells. Here, we present the protein-protein interaction network of TULP3, a protein that is responsible for the trafficking of G-protein-coupled receptors to cilia and whose ab ...[more]

PMID: 33187986

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