Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

IBD200: Multi-omics of IBD Severity Study

ABSTRACT: This study contains multiple -omic data sets. As a follow up to a study on 40 Ulcerative Colitis patients (MSV000082094), 210 fecal samples were analyzed through proteomics using Tandem Mass Tag (TMT) MS3 quantitation. Samples include both Ulcerative Colitis and Crohn's disease patients with healthy volunteers for context. Fecal samples were also analyzed by metabolomics through LCMS2 on a Bruker Maxis qTOF.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Bacteria Homo Sapiens (ncbitaxon:9606)

SUBMITTER: David Gonzalez

PROVIDER: MSV000086509 | MassIVE | Mon Nov 23 13:48:00 GMT 2020

REPOSITORIES: MassIVE

ACCESS DATA

Json Xml

Similar Datasets

Expression profiling in inflammatory bowel disease

Project description:The series was designed to identify new genes involved in the pathophysiology of inflammatory bowel disease (Crohn's disease and ulcerative colitis). This series represents a group of 31 samples, subdivided into 3 groups: 1) Normal controls: 11 samples; 2) patients with Crohn's diseases: 10 samples; 3) patients with ulcerative colitis: 10 samples. Each sample originated from a different patient or normal control, in total n=31 individuals were examined. Keywords = Inflammatory bowel disease Keywords = Crohn's disease Keywords = ulcerative colitis Keywords = expression screening Keywords = expression profiling Keywords: other

2005-08-11 | GSE1710 | GEO

UC_Severity_Multiomics

Project description:This study contains multiple omic data sets. Here we have data from a quantitative metaproteomic, metabolomic, and serum proteomic analysis of 40 patients with varying severity of Ulcerative Colitis. Fecal samples were analyzed through proteomics using TMT MS3 quantitation. Fecal samples were analyzed for metabolomics through LCMS2 on a Bruker Maxis qTOF. Samples were selected based on clinical endoscopic scores.

2018-02-23 | MSV000082094 | MassIVE

DNA methylation in peripheral blood from individuals with Crohns' disease or ulcerative colitis and normal controls

Project description:Genome wide DNA methylation profiling of Crohn's disease, ulcerative colitis, and normal peripheral blood samples. The Illumina Infinium HumanMethylation450 BeadChip v1.1 was used to obtain DNA methylation profiles across 482,421 CpGs in peripheral blood samples. Samples came from 17 Crohn's disease affected, 11 ulcerative colitis affected, and 20 normal individuals. Within these samples were three twin sets discordant for Crohn's disease and three twin sets discordant for ulcerative colitis.

2012-04-05 | GSE32148 | GEO

DNA methylation in a discovery cohort of colon mucosa samples from individuals with Crohns' disease or ulcerative colitis and normal controls

Project description:Genome wide DNA methylation profiling of Crohn's disease, ulcerative colitis, and normal colon mucosa samples. The Illumina Infinium HumanMethylation450 BeadChip v1.1 was used to obtain DNA methylation profiles across 482,421 CpGs in colon mucosa samples. Samples came from 10 Crohn's disease affected, 4 ulcerative colitis affected, and 10 normal individuals. One ulcerative colitis sample was assayed before and after treatment with 6-mercaptopurine and mesalamine.

2013-06-01 | GSE32146 | GEO

DNA methylation in a validation cohort of colon mucosa samples from individuals with Crohns' disease or ulcerative colitis and normal controls

Project description:Genome wide DNA methylation profiling of Crohn's disease, ulcerative colitis, and normal colon mucosa samples. The Illumina Infinium HumanMethylation450 BeadChip v1.1 was used to obtain DNA methylation profiles across 482,421 CpGs in colon mucosa samples. Samples came from 5 Crohn's disease affected, 5 ulcerative colitis affected, and 12 normal individuals. One ulcerative colitis sample was assayed before and after treatment with infliximab and mesalamine.

2015-01-01 | GSE42921 | GEO

DNA methylation in peripheral blood from individuals with Crohns' disease or ulcerative colitis and normal controls

2012-04-04 | E-GEOD-32148 | biostudies-arrayexpress

Transcription profiling of human healthy subjects, patients with Crohns Disease, and patients with Ulcerative Colitis to compare PBMCs in inflammatory bowel disease

Project description:Comparison of PBMC transcriptional profiles in healthy subjects, patients with Crohn's Disease, and patients with Ulcerative Colitis

2007-09-07 | E-GEOD-3365 | biostudies-arrayexpress

Transcriptome Profiling of Rectal and Ileal Tissues in Inflammatory Bowel Disease

Project description:We report whole mRNA gene expression and Percent Spliced In (PSI) estimates for rectal (n=59) and ileal (n=60) tissue samples of 33 patients with either Crohn's disease (n=19) or ulcerative colitis (n=14)

2020-10-08 | GSE158952 | GEO

Comparison of PBMCs in Inflammatory Bowel Disease

Project description:Comparison of PBMC transcriptional profiles in healthy subjects, patients with Crohn's Disease, and patients with Ulcerative Colitis Keywords: Disease state

2005-09-26 | GSE3365 | GEO

DNA methylation in colon mucosa samples from individuals with Crohns' disease or ulcerative colitis and normal controls

Project description:Genome wide DNA methylation profiling of Crohn's disease, ulcerative colitis, and normal colon mucosa samples. The Illumina Infinium HumanMethylation450 BeadChip v1.1 was used to obtain DNA methylation profiles across 482,421 CpGs in colon mucosa samples. Samples came from 9 Crohn's disease affected, 5 ulcerative colitis affected, and 10 normal individuals. Bisulfite converted DNA from the 24 samples were hybridized to the Illumina Infinium HumanMethylation450 BeadChip v1.1

2013-06-01 | E-GEOD-32146 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data