SPT5 licenses transition into productive transcription elongation by regulating promoter-proximal Pol II stability

ABSTRACT: An acute protein depletion system coupled with proteomic and genomic analyses reveal how SPT5 regulates promoter-proximal Pol II stability in eukaryotic cells, linking transcriptional initiation to productive elongation.

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Young Ah Goo  

PROVIDER: MSV000086806 | MassIVE | Thu Feb 04 13:22:00 GMT 2021

SECONDARY ACCESSION(S): PXD023997

REPOSITORIES: MassIVE