Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Eclipse, ultrafleXtreme
ORGANISM(S): Paraglaciecola Arctica (ncbitaxon:1128911)
SUBMITTER: Seokhee Kim
PROVIDER: MSV000088353 | MassIVE | Thu Nov 11 19:58:00 GMT 2021
REPOSITORIES: MassIVE
Biochemistry 20220121 3
Backbone <i>N-</i>methylation is one of the prominent peptide modifications that can greatly enhance the pharmacological properties of a peptide. Naturally occurring backbone <i>N-</i>methylated peptides are produced via nonribosomal or ribosomal pathways, the latter of which was only recently identified in the borosin family of ribosomally synthesized and post-translationally modified peptides. Although previous bioinformatic analyses have revealed new putative genes for borosin biosynthesis, t ...[more]