Proteomics

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Bothrops leucurus snake venom proteome


ABSTRACT: Bothrops leucurus is identified as a snake of medical interest in the State of Bahia, Brazil. However, so far, there are no studies that provide a refined mapping of the composition of this venom. The aim of this work was to deepen the knowledge of the toxins from the B. leucurus venom and to isolate and biologically characterize the most abundant toxin, a new basic PLA2 like. Shotgun proteomics approach identified 137 protein hits in B. leucurus venom subdivided into 19 protein families. These findings may enable the improvement of the clinical management of accidents caused by this snakebite.

INSTRUMENT(S): Q-Exactive (Thermo Fisher)

ORGANISM(S): Bothrops Leucurus (ncbitaxon:157295)

SUBMITTER: Ilka Borges Biondi   Lucilene Delazari dos Santos  

PROVIDER: MSV000088552 | MassIVE | Fri Dec 10 05:11:00 GMT 2021

REPOSITORIES: MassIVE

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