Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Proteomics analysis of FFPE AIS thrombi

ABSTRACT: We analysed 31 formalin-fixed paraffin-embedded (FFPE) acute ischemic stroke thrombi of cardioembolic and atheroembolic etiology using a shotgun proteomic approach. Here we share the mass spec raw files of each sample to contribute to the investigation of thrombus proteome.

INSTRUMENT(S): Q-Orbitrap

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Karen Doyle

PROVIDER: MSV000088792 | MassIVE | Mon Feb 07 06:25:00 GMT 2022

SECONDARY ACCESSION(S): PXD031477

REPOSITORIES: MassIVE

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Formalin-fixed paraffin-embedded (FFPE) ring trial

Project description:Formalin-fixed paraffin-embedded (FFPE) ring trial

| PRJEB32144 | ENA

Gene expression profiling of FFPE kidney cancer samples

Project description:We used Illumina microarrays to profile RNA expression in formalin-fixed paraffin-embedded (FFPE) samples of 22 metastatic or advanced RCC cases.

2021-07-28 | GSE180925 | GEO

Ring Trial 2019 FFPE

Project description:Ring Trial 2019 on formalin-fixed paraffin-embedded (FFPE) material

| PRJEB32142 | ENA

Gene Expression Profiling of Chronically Inflamed FFPE Placental Tissue

Project description:The aim of this research was to explore gene expression changes in chronically inflammed placental tissue This study compared FFPE tissue with and without chronic placental inflammation, manifested as overlapping chronic chorioamnionitis, chronic villitis of unknown etiology, and chronic deciduitis. RNA expression profiling was conducted on formalin fixed, paraffin embedded placental tissue using Illumina microarrays. To further explore and validate gene expression findings, we conducted immunohistochemical assessment of protein level expression.

2015-09-01 | E-GEOD-68474 | biostudies-arrayexpress

Expanding epigenomics to archived FFPE tissues: An evaluation of DNA repair methodologies

Project description:A study to evaluate techniques for repairing DNA from formalin-fixed paraffin-embedded (FFPE) tissue samples by direct comparison of FFPE DNA repair methods prior to analysis on genome-wide methylation array to matched fresh frozen (FF) tissues. Formalin-fixed paraffin-embedded tissue from three colon adenocarcinoma samples were subjected to different FFPE-oriented DNA repair approaches and sequences, then compared with corresponding fresh frozen tissues. All samples were hybridized to the Illumina Infinium 450k Human Methylation BeadChip.

2014-12-17 | E-GEOD-59038 | biostudies-arrayexpress

Expanding epigenomics to archived FFPE tissues: An evaluation of DNA repair methodologies

2014-12-17 | GSE59038 | GEO

Expression profiling of formalin-fixed, paraffin-embedded (FFPE) breast cancer metastases of the lymph node and autopsy tissues

Project description:This SuperSeries is composed of the following subset Series: GSE32488: Expression profiling of formalin-fixed, paraffin-embedded (FFPE) breast cancer metastases of the lymph node and autopsy tissues [DASL HT-12 samples] GSE32489: Expression profiling of formalin-fixed, paraffin-embedded (FFPE) breast cancer metastases of the lymph node and autopsy tissues [DASL HumanRef-v3 samples] Refer to individual Series

2012-10-02 | E-GEOD-32490 | biostudies-arrayexpress

Transcription profiling by array of formalin-fixed and paraffin-embedded (FFPE) tumor samples.

Project description:Transcription profiling by array of formalin-fixed and paraffin-embedded (FFPE) tumor samples.

2013-06-21 | E-MTAB-990 | biostudies-arrayexpress

Comparison of miRNA expression between primary tissue, patient-derived cancer model, and FFPE tissue

Project description:We investigated whether we could use RNA from tumor purified formalin-fixed paraffin-embedded (FFPE) tissue for small RNA sequencing to obatin comparable results to RNA from the primary tumor.

2023-11-01 | GSE212812 | GEO

An array based analysis of miRNA expression comparing matched frozen and FFPE human tissue samples

Project description:MicroRNAs (miRNAs) are small non-coding RNAs that repress gene expression at the post transcriptional level via an antisense RNA-RNA interaction. Generally, miRNAs derived from snap frozen or fresh samples are used for array based profiling. Since tissues in most pathology departments are available only in formalin fixed and paraffin embedded state, we sought to evaluate the miRNA derived from formalin fixed and paraffin embedded (FFPE) samples for microarray analysis. In this study, miRNAs extracted from matched snap frozen and FFPE samples were profiled using the Agilent miRNA array platform. Each miRNA sample was hybridized to arrays containing probes interrogating 470 human miRNAs. A total of seven cases were compared in either duplicate or triplicate. Intrachip and interchip analyses demonstrated that the processes of miRNA extraction, labeling and hybridization from both frozen and FFPE samples are highly reproducible and add little variation to the results, as technical replicates showed high correlations (Kendall tau=0.722-0.853, Spearman rank correlation coefficient=0.891-0.954). Our results showed consistent high correlation between matched frozen and FFPE samples (Kendall tau=0.669-0.815, Spearman rank correlation coefficient=0.847-0.948), supporting the use of FFPE-derived miRNAs for profiling. Keywords: formalin-fixed and paraffin-embedded (FFPE) miRNA profiling

2008-11-01 | GSE12458 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data