Dataset Information
Spatial evaluation of transcriptomic and proteomic data in ALK rearranged lung cancer - a pilot study
Ontology highlight
ABSTRACT:
INSTRUMENT(S): maXis II
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER: 
A. Marcell Szasz (szaszam@gmail.com)
PROVIDER: MSV000089286 | MassIVE | Wed Apr 20 14:00:00 BST 2022
REPOSITORIES: MassIVE
Publications
Inter- and intratumoral proteomics and glycosaminoglycan characterization of ALK rearranged lung adenocarcinoma tissues: a pilot study.
Scientific reports 20230417 1
Lung cancer is one of the most common types of cancer with limited therapeutic options, therefore a detailed understanding of the underlying molecular changes is of utmost importance. In this pilot study, we investigated the proteomic and glycosaminoglycan (GAG) profile of ALK rearranged lung tumor tissue regions based on the morphological classification, mucin and stromal content. Principal component analysis and hierarchical clustering revealed that both the proteomic and GAG-omic profiles are ...[more]
