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Clostridium autoethanogenum isopropanol production via native plasmid pCA replicon

ABSTRACT: Clostridium autoethanogenum isopropanol production via native plasmid pCA replicon

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Clostridium Autoethanogenum (ncbitaxon:84023)

SUBMITTER: Steven Brown

PROVIDER: MSV000089452 | MassIVE | Tue May 10 14:57:00 BST 2022

SECONDARY ACCESSION(S): PXD033792

REPOSITORIES: MassIVE

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Clostridium autoethanogenum isopropanol production via native plasmid pCA replicon.

Nogle Robert R Nagaraju Shilpa S Utturkar Sagar M SM Giannone Richard J RJ Reynoso Vinicio V Leang Ching C Hettich Robert L RL Mitchell Wayne P WP Simpson Sean D SD Jewett Michael C MC Köpke Michael M Brown Steven D SD

Frontiers in bioengineering and biotechnology 20220805

Clostridium autoethanogenum is a model gas-fermenting acetogen for commercial ethanol production. It is also a platform organism being developed for the carbon-negative production of acetone and isopropanol by gas fermentation. We have assembled a 5.5 kb pCA plasmid for type strain DSM10061 (JA1-1) using three genome sequence datasets. pCA is predicted to encode seven open-reading frames and estimated to be a low-copy number plasmid present at approximately 12 copies per chromosome. RNA-s ...[more]

PMID: 36032736

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