Mablango_ClpP_HYTANE_P124_Lumos

ABSTRACT: This dataset consists of 6 raw MS files, acquired on Thermo Fusion Lumos mass spectrometer operated in Data Dependent Acquisition mode. Samples were generated by Keith Wong. Sample processing and mass spectrometry acquisition was performed by Cassandra Wong. Data analysis was performed by Cassandra Wong, Shen Zhang and Keith Wong. The files are associated with a manuscript submitted for publication by Mark Mabanglo et al. The main goal of this paper was to demonstrate the use of novel imipridone derived compounds to induce selective cancer cell lethality via dysregulation of ClpP in cancer cells. Walid Houry is the corresponding author of the manuscript ([e-mail]); Anne-Claude Gingras should be contacted for questions on this dataset ([e-mail]) This submission is associated with 4 Supplementary Files (in addition to this README file) Metadata describes the composition of this dataset. Peptides lists all peptide identification evidence. Proteins lists all protein identification evidence. Pvalue_peptides lists all p-values calculated between conditions for peptides.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Anne-Claude Gingras  

PROVIDER: MSV000089642 | MassIVE | Mon Jun 13 11:16:00 BST 2022

REPOSITORIES: MassIVE