Dataset Information

Thermal proteome profiling reveals distinct target selectivity for differentially oxidized oxysterols

ABSTRACT: The dataset contains mass spectrometric raw data from Thermal Proteomic Profiling experiments aimed to identify the protein targets of three A- and B-ring oxidized sterols (cholestane-3beta,5alfa,6beta-triol (CT), 7keto-cholesterol (7-KC), 4beta-hydroxycholesterol (4beta-HC) ) and a side-chain oxidized sterol (25-hydroxycholesterol (25-HC)). The dataset comprises the raw data for the 4 different oxysterols, measured on both oxysterol (compound) and DMSO (vehicle), each collected in 28 fractions. The experiments were performed in three independent replicates for each oxysterol (R1-R3).

INSTRUMENT(S): Q-Exactive HF-X (Thermo Fisher)

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: CECILIA ROSSETTI