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Engineering Transcriptional Regulation of Pentose Metabolism in Rhodosporidium toruloides for Improved Conversion of Xylose to Bioproducts

ABSTRACT: Discovery proteomics on three R. toruloides strains with differing Pnt1 expression (WT IFO 0880, OE-Pnt1, and delta Pnt1) grown on either xylose or xylose and glycerol at mid-log phase.

INSTRUMENT(S): Q Exactive HF-X

ORGANISM(S): Rhodosporidium Toruloides Np11 (ncbitaxon:1130832)

SUBMITTER: Kristin E. Burnum-Johnson

PROVIDER: MSV000089938 | MassIVE | Thu Jul 21 11:25:00 BST 2022

SECONDARY ACCESSION(S): PXD035507

REPOSITORIES: MassIVE

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Publications

A deep redox proteome profiling workflow and its application to skeletal muscle of a Duchenne Muscular Dystrophy model.

Day Nicholas J NJ Zhang Tong T Gaffrey Matthew J MJ Zhao Rui R Fillmore Thomas L TL Moore Ronald J RJ Rodney George G GG Qian Wei-Jun WJ

Free radical biology & medicine 20221025 Pt 1

Perturbation to the redox state accompanies many diseases and its effects are viewed through oxidation of biomolecules, including proteins, lipids, and nucleic acids. The thiol groups of protein cysteine residues undergo an array of redox post-translational modifications (PTMs) that are important for regulation of protein and pathway function. To better understand what proteins are redox regulated following a perturbation, it is important to be able to comprehensively profile protein thiol oxida ...[more]

PMID: 36306991

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