The proteome landscape of genome-wide genetic perturbations

ABSTRACT: Despite the massive research efforts of the post-genomics era, a significant fraction of genes remain without functional annotation. Proteomics holds the promise to close significant gaps, but has only recently reached the scalability and precision of genome-scale studies. Here we combine large-scale proteomics with functional genomics and use a streamlined platform for fast yeast proteomics to record quantitative proteomes of ~4,500 single knock-out strains of a genome-scale yeast knock-out collection.

INSTRUMENT(S): TripleTOF 6600

ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932)

SUBMITTER: Prof. Dr. Markus Ralser  

PROVIDER: MSV000090136 | MassIVE | Mon Aug 15 11:06:00 BST 2022

SECONDARY ACCESSION(S): PXD036062

REPOSITORIES: MassIVE