Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transforming vs. non-transforming lichen planus proteomics

ABSTRACT: Proteomics of transforming vs. non-transforming lichen planus.

INSTRUMENT(S): QExactive

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Dr.Julia Lehman

PROVIDER: MSV000090139 | MassIVE | Mon Aug 15 17:56:00 BST 2022

REPOSITORIES: MassIVE

ACCESS DATA

Json Xml

Similar Datasets

Swarming sample vs non-swarming sample

Project description:Swarming sample vs non-swarming sample

| PRJNA634263 | ENA

Proteomics profiling of sera from normoglycaemic twins for which the body mass index is known

Project description:Bead-based proteomics MolPAGE study using sera from normoglycaemic twins

2008-11-02 | E-TABM-370 | biostudies-arrayexpress

Integrative proteomics reveals increased non-degradative ubiquitylation during CD4+ T cell activation

Project description:Integrative proteomics reveals increased non-degradative ubiquitylation during CD4+ T cell activation

| PRJNA526619 | ENA

insulin resistant duodenum vs. non-insulin resistant duodenum

Project description:insulin resistant duodenum vs. non-insulin resistant duodenum

| PRJNA615363 | ENA

Integrative proteomics reveals increased non-degradative ubiquitylation during CD4+ T cell activation

Project description:In spite of gathering evidence that ubiquitylation can direct non-degradative outcomes, most investigations of ubiquitylation in T cells remain focused on degradation. Here we integrated proteomic and transcriptomic datasets to establish a framework for predicting degradative or non-degradative outcomes of ubiquitylation in primary CD4+ T cells. Di-glycine remnant proteomics revealed ubiquitylated proteins, while whole cell proteomic and transcriptomic data were used to predict whether ubiquitylated proteins showed evidence of degradation. Applying this analysis to ubiquitylated proteins with functions in TCR signaling led us to the prediction that early T cell activation promotes increased non-degradative ubiquitylation. Supporting this, we observed an increase in non-proteasome targeted K29, K33 and K63 polyubiquitin chains during T cell activation, while K48 chains appeared unchanged. This study reveals over 1,200 proteins that are ubiquitylated in primary CD4+ T cells and supports the relevance of non-proteasomally targeted ubiquitin chains in T cell signaling.

2020-03-11 | GSE128154 | GEO

M/D-tumors vs non´-tumor mammary gland tissues

Project description:M/D-tumors vs non´-tumor mammary gland tissues

| PRJNA635111 | ENA

CYGB+ expressing vs non cytoglobin expressing cells (NCE) (MOCK)

Project description:CYGB+ expressing vs non cytoglobin expressing cells (NCE) (MOCK)

| PRJNA540265 | ENA

iTRAQ proteomics of non fibrotic carcinoma on Human Liver

Project description:We present a study of hepatocellular carcinoma developed on non-fibrotic liver (nfHCC) that combines complementary quantitative iTRAQ-based proteomics and phosphoproteomics approaches. Using both approaches, we analyzed a set of 24 samples (18 nfHCC vs 6 non-tumor liver tissue).

2014-09-18 | PXD001253 | Pride

insulin resistant duodenum vs. non-insulin resistant duodenum

Project description:Transcriptional profiling of duodenum from non-obese patients and patients with morbid obesity comparing non-insulin resistance vs. insulin resistande. Goal was to determine the involvement of the duodenum in the development of insulin resistance and the possible influence of obesity.

2022-06-01 | GSE147562 | GEO

mRNA expression data of Mes vs. Epi cells in mouse non-NE SCLC

Project description:Distinct mRNA populatins have been detected in Epi vs. Mes cells of mouse non-NE SCLC The aim of the study was to globally profile the differential gene expression in Mes vs. Epi cells of mouse non-NE SCLC.

2024-03-11 | GSE168709 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data