The human cerebrospinal fluid lipoproteome
Ontology highlight
ABSTRACT: Lipoproteins in human cerebrospinal fluid (CSF-Lps) were exchange labeled with a rhodamine-containing phospholipid and size distribution determined using a fluorescent lipoprotein profiler. CSF-Lps within each fraction were isolated using lipid removal agent. Lipid-bound proteins were digested directly off the resin, collected, and analyzed using bottom-up mass spectrometry (LC-MS/MS). Computational analysis of protein abundance and co-migration patterns were used to generate protein network maps and identify potential CSF-Lp subspecies.
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER:
John T. Melchior
PROVIDER: MSV000091813 | MassIVE | Thu Apr 27 10:18:00 BST 2023
REPOSITORIES: MassIVE
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