Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Exploris 480
ORGANISM(S): Mus <mouse, Genus> (ncbitaxon:10088) Homo Sapiens (ncbitaxon:9606)
SUBMITTER: Jian Cai
PROVIDER: MSV000092063 | MassIVE | Wed May 31 10:00:00 BST 2023
REPOSITORIES: MassIVE
Cai Jian J Song Ming M Li Ming M Merchant Michael M Benz Frederick F McClain Craig C Klein Jon J
Journal of proteome research 20231229 2
Protein S-acylation is a reversible post-translational modification (PTM). It is present on diverse proteins and has important roles in regulating protein function. Aminolysis with hydroxylamine is widely used in the global identification of the PTM. However, the identification is indirect. Distinct criteria have been used for identification, and the false discovery rate has not been addressed. Here, we report a site-specific method for S-acylation identification based on tagging of S-acylation ...[more]