Proteomics

Dataset Information

0

Data files for site specific S-acylation


ABSTRACT: Raw data files for site specific S-acylation identification.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Mus <mouse, Genus> (ncbitaxon:10088) Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Jian Cai  

PROVIDER: MSV000092063 | MassIVE | Wed May 31 10:00:00 BST 2023

REPOSITORIES: MassIVE

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Publications

Site-Specific Identification of Protein S-Acylation by IodoTMT0 Labeling and Immobilized Anti-TMT Antibody Resin Enrichment.

Cai Jian J   Song Ming M   Li Ming M   Merchant Michael M   Benz Frederick F   McClain Craig C   Klein Jon J  

Journal of proteome research 20231229 2


Protein S-acylation is a reversible post-translational modification (PTM). It is present on diverse proteins and has important roles in regulating protein function. Aminolysis with hydroxylamine is widely used in the global identification of the PTM. However, the identification is indirect. Distinct criteria have been used for identification, and the false discovery rate has not been addressed. Here, we report a site-specific method for S-acylation identification based on tagging of S-acylation  ...[more]

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