Selective inhibition of OSBP blocks retrograde trafficking by inducing partial Golgi degradation

ABSTRACT: The dataset contains mass spectrometric raw data from two series of TMT-based expression proteomics aimed at studying the selectivity profile of oxybipin-2 and proteins affected under the treatment of OSBP inhibitors. The dataset comprises the raw data for the ITDRF of oxybipin-2 at 4 different concentrations (TMTpro, processed by Proteome Discoverer), 4 OSBP inhibitors such as C3 and OSW-1 (TMTpro, processed by Proteome Discoverer) measured on both tested-compounds and DMSO (vehicle), each collected in 30 fractions. The experiments were performed in three independent replicates for each compound (R1-R3).

INSTRUMENT(S): Q-Exactive HF-X (Thermo Fisher)

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Luca laraia  

PROVIDER: MSV000093086 | MassIVE | Thu Oct 12 02:47:00 BST 2023

REPOSITORIES: MassIVE