Contaminant Spot Check and Removal Assay (ContamSPOT) for Mass Spectrometry Analysis

ABSTRACT: Mass spectrometry (MS) analysis is often challenged by unexpected contaminations from detergents, salts, and polymers that compromise the data quality and damage the chromatography and mass spectrometry instruments. However, there is no existing contaminant assay to test and quantify contaminants prior to MS analysis. Here, we developed a rapid and sensitive contaminant spot check and removal assay (ContamSPOT) to detect and quantify trace amounts of contaminants, such as detergents, salts, and other chemicals commonly used in MS sample preparation workflow.

INSTRUMENT(S): Q Exactive HF-X

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Ling Hao  

PROVIDER: MSV000093387 | MassIVE | Mon Nov 13 15:57:00 GMT 2023

REPOSITORIES: MassIVE