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Top-Down Proteomic Analysis of Limited Samples Using Porous Layer Open Tubular Columns and High-Field Asymmetric Ion Mobility Spectrometry Coupled to Mass Spectrometry

ABSTRACT: Here we explored the potential of a novel platform based on ultra-low flow porous layer open tubular (PLOT) columns and high-field asymmetric waveform ion mobility spectrometry (FAIMS) interfaced with an ultrasensitive mass spectrometry (MS)-based technology in top-down proteomic analysis of a low number of mammalian cells.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Alexander R Ivanov

PROVIDER: MSV000093622 | MassIVE | Sat Dec 09 18:25:00 GMT 2023

REPOSITORIES: MassIVE

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