Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Comprehensive whole proteome analysis in response to YIPF5 depletion or mutation

ABSTRACT: Surfaceome analysis was performed on MCF10A cells under various conditions, including wild-type (wt), YIPF5-depleted, YIPF5-mutated, and cells with re-expression of wild-type YIPF5. The primary objective was to discern differences in the composition of surface proteins in response to YIPF5 depletion or mutation. Additionally, a comprehensive whole proteome analysis was carried out to provide a comprehensive overview of the proteomic landscape in the analyzed cells.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Christoph Kaether

PROVIDER: MSV000093778 | MassIVE | Fri Jan 05 14:58:00 GMT 2024

SECONDARY ACCESSION(S): PXD048288

REPOSITORIES: MassIVE

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Differences in the composition of surface proteins in response to YIPF5 depletion or mutation

Project description:Surfaceome analysis was performed on MCF10A cells under various conditions, including wild-type (wt), YIPF5-depleted, YIPF5-mutated, and cells with re-expression of wild-type YIPF5. The primary objective was to discern differences in the composition of surface proteins in response to YIPF5 depletion or mutation. Additionally, a comprehensive whole proteome analysis was carried out to provide a comprehensive overview of the proteomic landscape in the analyzed cells.

2024-01-04 | MSV000093771 | MassIVE

Alterations in the secretome composition arising from YIPF5 depletion or mutation

Project description:Secretome analysis was conducted on MCF10A cells with various conditions, including wild-type (wt) cells, YIPF5-depleted cells, cells with mutated YIPF5, and cells with re-expression of wild-type YIPF5. The primary objective was to discern alterations in the secretome composition arising from YIPF5 depletion or mutation. This investigation aimed to shed light on the influence of YIPF5 on the secretory profile of MCF10A cells, providing insights into potential changes in extracellular signaling and cellular communication associated with YIPF5 status.

2024-01-04 | MSV000093769 | MassIVE

Identifying transcripts that are transcriptinoally regulated by CBFB and RUNX1 using RNAseq

Project description:Using RNAseq to identify differentially expressed transcripts between CBFB wild type (WT) and knockout (KO) or between RUNX1 wild type (WT) and knockout (KO) MCF10A cells.

2019-04-18 | GSE120216 | GEO

Lasp1 gene deletion: Effect on gene expression in the gastric mucosa

Project description:Comparative analysis of gene expression in murine gastric fundic mucosa in wild-type and Lasp1-null littermates. The data provide a comprehensive overview of genes expressed in the mouse gastric mucosa and show that the expression of several known and unidentified genes is modified by disruption of the Lasp1 gene. Keywords: Genotypic comparison

2009-02-13 | GSE14813 | GEO

CC10 gene deletion: Effect on gene expression in the sinonasal mucosa

Project description:Comparative analysis of gene expression in murine sinonasal mucosa in wild-type and CC10-knockout littermates with allergic eosinophilic chronic rhinosinusitis. The data provide a comprehensive overview of genes expressed in the mouse sinonasal mucosa and show that the expression of several known and unidentified genes is modified by disruption of the CC10 gene.

2010-12-01 | GSE20969 | GEO

Genome-wide characterization of the transcriptional program of Myc-dependent transformation, ChIP-chip

Project description:We profiled Myc binding in a normal breast cell-line (MCF10A) under basal conditions after ectopic expression of Myc. We showed that ectopic Myc expression increases tumour formation in vivo and in vitro. We then profiled genome-wide Myc binding using Agilent promoter arrays in MCF10A cells expressing wild-type and ectopic Myc. We show that Myc binds to a greater number of spots in wild-type than in Myc cells, but that some targets are unique to each condition. Keywords: ChIP-chip

2009-11-24 | GSE13749 | GEO

HOXA5 depletion in MCF10A cells

Project description:Microarray analysis of gene expression in MCF10A cells following HOXA5 depletion.

2016-02-01 | GSE75840 | GEO

Genome-wide characterization of the transcriptional program of Myc-dependent transformation, expression study

2009-11-24 | GSE14263 | GEO

Genome-wide characterization of the transcriptional program of Myc-dependent transformation

2009-11-24 | GSE14264 | GEO

Genome-wide mapping of OsHOX24-binding sites in rice

Project description:In this study, we provide a global overview of genome-wide OsHOX24 binding sites in rice under control and desiccation stress conditions in wild-type and OsHOx24 overexpressing rice plants (H49 line) via chromatin immunoprecipitation sequencing (ChIP-sequencing) approach. We identified numerous downstream targets of OsHOX24 under desiccation stress and control by analyzing the comprehensive binding site map of OsHOX24 at whole genome level in rice.

2021-04-04 | GSE144419 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data