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Electron transport chain inhibition increases cellular dependence on purine transport and salvage

ABSTRACT: H460 cells were treated with vehicle or IACS for 24 hours followed by protein isolation and TMT10plex labelling. Samples with TMT labels 126, 127N, 127C, 128N, 128C were treated with vehicle (or DMSO), and samples with TMT labels 129N, 129C, 130N, 130C, and 131 were treated with IACS-010759.

INSTRUMENT(S): Orbitrap Eclipse

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Ralph DeBerardinis

PROVIDER: MSV000094553 | MassIVE | Tue Apr 16 10:55:00 BST 2024

REPOSITORIES: MassIVE

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Electron transport chain inhibition increases cellular dependence on purine transport and salvage.

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