Proteomics

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A. muciniphila, B. longum, E. coli, headspace metabolites


ABSTRACT: Culture headspaces of A. muciniphila, B. longum, E. coli, and sterile media controls using sorbent tubes and GCMS (Figure 3C)

INSTRUMENT(S): Pegasus 4D

ORGANISM(S): Bifidobacterium Longum Subsp. Longum (ncbitaxon:1679) Escherichia Coli (ncbitaxon:562) Bhi-mucin Akkermansia Muciniphila (ncbitaxon:239935)

SUBMITTER: Audrey Odom John   Andrew L. Kau  

PROVIDER: MSV000095341 | MassIVE | Mon Jul 15 13:51:00 BST 2024

REPOSITORIES: MassIVE

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Publications


The gut microbiota is crucial to health, yet implementation of microbiota-based therapeutics is limited by the lack of rapid diagnostics. We hypothesize that breath contains gut microbe-derived volatile organic compounds (VOCs) reflecting microbiota composition and metabolism. In healthy children, we found that breath VOC composition (or volatilome), assessed by gas chromatography-mass spectrometry, correlates with gut microbiome composition and function. By capturing exhaled breath from human-s  ...[more]

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