Label-free global proteome profiling of European American and African American bladder tumor patients.

ABSTRACT: Bladder cancer (BLCA) mortality is higher in African American (AA) patients compared to their European American (EA) counterparts, but the molecular mechanism underlying differences are unknown. . Thus, we performed proteomics analysis of AA and EA BLCA and identified higher mitochondrial OXPHOS specifically through complex I activation in AA BLCA.

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Sung Yun Jung  

PROVIDER: MSV000095559 | MassIVE | Thu Aug 08 17:00:00 BST 2024

SECONDARY ACCESSION(S): PXD054731

REPOSITORIES: MassIVE