Mining Yeast Diversity Unveils Novel Targets for Improved Heterologous Laccase Production in Saccharomyces cerevisiae
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ABSTRACT:
INSTRUMENT(S): timsTOF Pro 2
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932)
SUBMITTER: 
Thibault Mayor
PROVIDER: MSV000095757 | MassIVE |
REPOSITORIES: MassIVE
Publications
Mining yeast diversity unveils novel targets for improved heterologous laccase production in Saccharomyces cerevisiae.
Wong Ryan Wei Kwan RWK Foo Marissa M Lay Jasmine R S JRS Wai Tiffany L T TLT Moore Jackson J Dutreux Fabien F Molzahn Cristen C Nislow Corey C Measday Vivien V Schacherer Joseph J Mayor Thibault T
Microbial cell factories 20250310 1
The budding yeast Saccharomyces cerevisiae is a widely utilized host cell for recombinant protein production due to its well studied and annotated genome, its ability to secrete large and post-translationally modified proteins, fast growth and cost-effective culturing. However, recombinant protein yields from S. cerevisiae often fall behind that of other host systems. To address this, we developed a high-throughput screen of wild, industrial and laboratory S. cerevisiae isolates to identify stra ...[more]
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