COOKIE-Pro: Covalent Inhibitor Binding Kinetics Profiling on the Proteome Scale

ABSTRACT: COOKIE-Pro mass spec dataset collected from Orbitrap Lumos for spebrutinib SB2 (20231129_Speb_SB2_TMT18_ScaleUp_MS2_8ul.mzML; Ascend_VQneo_ES75500_SP2_X.mzML) and ibrutinib IB-C8-DTB (Lang_HFL_IB_COOKIE_X). Two-point COOKIE-Pro data are collected form Orbitrap Ascend, named as "Ascend_VQneo_ES75500_FAIMS_MS2_COOKIEX_Y". Two-point COOKIE-Pro data are searched with dynamic modification of unimod:1 (Carbamidomethyl) and unimod:2062 (DBIA) on cysteine.

INSTRUMENT(S): Orbitrap Fusion Lumos, Orbitrap Ascend

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Jin Wang  

PROVIDER: MSV000095804 | MassIVE |

REPOSITORIES: MassIVE