Mechanism of allosteric activation in human mitochondrial ClpP protease

ABSTRACT: Continuous labelling HDX on WT ClpP and ClpP_extended, in apo and bortezomib-bound states. Pulse labelling HDX on WT ClpP and ClpP_extended, 1, 30, 180 minutes post a 100X dilution, samples were subjected to D2O-based buffer for 10 s. Folders for each experiment are organized per state, and time points. Peptide mapping and undeuterated controls are included.

INSTRUMENT(S): Synapt G2-S HDMS

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Dr. Siavash Vahidi  

PROVIDER: MSV000095957 | MassIVE |

REPOSITORIES: MassIVE