Lysosomal protein atlas of brain cell types identifies SLC45A1-associated disease as a lysosomal disorder
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ABSTRACT: LysoIP experiment using different Cre-lines to characterize the lysosomal content of the brain. Using Syn1-Cre (Neurons), Gfap-Cre (Astrocytes), Olig2-Cre (Oligodendrocytes) and Cx3cr1-Cre (Microglia) mouse lines, to understand by MS the different composition.
INSTRUMENT(S): Orbitrap Exploris 480, nanoACQUITY UPLC System with 1D Technology, Q-Exactive HF (Thermo Scientific instrument)
ORGANISM(S): Mus Musculus (ncbitaxon:10090)
SUBMITTER:
Alessandro Ori
PROVIDER: MSV000096018 | MassIVE | Thu Oct 03 07:27:00 BST 2024
SECONDARY ACCESSION(S): PXD056481
REPOSITORIES: MassIVE
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