Proteomics

Dataset Information

0

CYP1B1-AS1 regulates CYP1B1 to promote Coxiella burnetii pathogenesis by inhibiting ROS and host cell death

ABSTRACT: ECL1_1173151: FLAG-IP, HEK293T transfected with pcDNA3.1 vector expressing N-term-3XFLAG tagged GFP ECL1_1173152: FLAG-IP, HEK293T transfected with pcDNA3.1 vector expressing N-term-3XFLAG tagged GFP ECL1_1173153: FLAG-IP, HEK293T transfected with pcDNA3.1 vector expressing N-term-3XFLAG tagged CYP1B1 ECL1_1173154: FLAG-IP, HEK293T transfected with pcDNA3.1 vector expressing N-term-3XFLAG tagged CYP1B1 ECL1_1173155: FLAG-IP, HEK293T transfected with pcDNA3.1 vector expressing N-term-3XFLAG tagged CYP1B1 and infected with C.burnetii NMII ECL1_1173156: FLAG-IP, HEK293T transfected with pcDNA3.1 vector expressing N-term-3XFLAG tagged CYP1B1 and infected with C.burnetii NMII

INSTRUMENT(S): Orbitrap Eclipse

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Coxiella Burnetii (ncbitaxon:777)

SUBMITTER: James E. Samuel  

PROVIDER: MSV000096725 | MassIVE | Mon Dec 23 09:48:00 GMT 2024

REPOSITORIES: MassIVE

Json Xml

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1
altmetric image

Publications

CYP1B1-AS1 regulates CYP1B1 to promote <i>Coxiella burnetii</i> pathogenesis by inhibiting ROS and host cell death.

Arunima Aryashree A   Niyakan Seyednami S   Butler Samantha M SM   Clark Sabrina D SD   Pinson Anna A   Kwak Doyoung D   Qian Xiaoning X   de Figueiredo Paul P   van Schaik Erin J EJ   Samuel James E JE  

Research square 20241211

<i>Coxiella burnetii</i> (Cb), the causative agent of Q fever, replicates within host macrophages by modulating immune responses through poorly understood mechanisms. Long non-coding RNAs (lncRNAs) are emerging as critical regulators of inflammation, yet their role in Cb pathogenesis remains largely unexplored. Here, we employed a global transcriptomic approach to identify lncRNAs specific to Cb infection in THP-1 derived macrophages, compared to 15 other microbial infections. CYP1B1-AS1 was uni  ...[more]

Similar Datasets

Proteomics The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells
2019-04-18 | PXD012669 | Pride
Proteomics HERD-1 Flag IP mass data in C.elegans
2024-07-14 | PXD051885 | Pride
Transcriptomics UV cross-linking RIP-seq of VSV-GFP-infected HEK293T cells overexpressed PTENα
2024-02-19 | GSE218439 | GEO
Transcriptomics RNA helicase DDX5-induced circPHF14 promotes gastric cancer cell progression
2023-04-26 | GSE207636 | GEO
Transcriptomics miRNA arrays: Ago2 transfected vs. Mock, Ago2 IP vs. total RNA
2008-04-08 | GSE11081 | GEO
Proteomics Identification and functional characterization of NCoR1-interacting proteins associated with mitochondrial biogenesis
2023-07-20 | PXD040945 | Pride
Proteomics Mass spectrometry runs and analysis of host proteins co-immunoprecipitated with RABV M protein
2021-09-09 | PXD021039 | Pride
Transcriptomics Identify Flag-bound transcripts via RIP-seq
2021-10-28 | GSE182620 | GEO
Transcriptomics LIN-41 RIP-Seq
2018-04-25 | GSE106814 | GEO
Other Identify METTL3, 14 and 16-bound transcripts via RIP-seq
2021-10-28 | GSE156797 | GEO