Rational design of potent small molecule SMARCA2/A4 (BRM/BRG1) degraders
Ontology highlight
ABSTRACT: Target-anchored monovalent degraders are more drug-like than their bivalent counterparts, Proteolysis Targeting Chimeras (PROTACs), while offering greater target specificity control than the E3 ligase anchored monovalent degraders, also known as molecular glues.
INSTRUMENT(S): Orbitrap Eclipse
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER:
Hanna Budayeva
PROVIDER: MSV000096813 | MassIVE | Thu Jan 09 13:55:00 GMT 2025
REPOSITORIES: MassIVE
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