Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

A.flavus-population-strains-metabolomics-negative

ABSTRACT: Chemical innovation is essential for fungi to adapt to ever-changing environments. However, the role of genetic and environmental interactions in driving fungal metabolic differentiation remains ambiguous. Here, we studied the phylogeographic diversity of a panel of 1,052 Aspergillus flavus strains across four continents, including 544 newly sequenced strains from China that revealed new global subpopulations. The population diversity of A. flavus shows strong phylogeographic metabolic patterns, with different clades being associated with specific environments.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Aspergillus Flavus (ncbitaxon:5059)

SUBMITTER: huali xie

PROVIDER: MSV000096982 | MassIVE | Tue Jan 28 15:22:00 GMT 2025

REPOSITORIES: MassIVE

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Mechanism for microbial population collapse in a fluctuating resource environment

Project description:Shotgun proteomics of Desulfovibrio vulgaris and Methanococcus maripaludis co-cultures within dynamically changing environments that support sulfate respiration or syntrophy.

2016-11-28 | MSV000080363 | MassIVE

Comparative genomics analysis of Aspergillus glaucus CCHA provides insights into the adaptation of stress response

Project description:Aspergillus display an amazing level of diversity in physiologies, and environments that they occupy. Strategies for coping with diverse environmental stresses have evolved in different Aspergillus species. Therefore, Aspergillus are considered to be good models for investigating the adaptation and response to many natural and anthropogenic environmental stressors. Recent genome sequencing projects in several Aspergillus have provided insights into the molecular and genetic mechanisms underlying their responses to some environmental stressors. However, to better clarify the conserved and differentiated features of the adaptive response to specific stresses and to trace the evolutionary process of environmental adaptation and response in Aspergillus, insight from more Aspergillus species with different evolutionary positions, such as A. glaucus, and thus offer a large number of models of adaptation and response to various environmental stresses. Here, we report a high-quality reference genome assembly of A. glaucus CCHA from the surface of wild vegetation around saltern of Jilin, China, based on sequence data from whole-genome shotgun (WGS) sequencing platforms of Illumina solexa technologies. This assembly contains 106 scaffolds ( >1 Kb; N50 = ~0.795 Mb), has a length of ~28.9 Mb and covers ~97% of the predicted genome size (~120 Mb). Together with the data analyses from comprehensive transcriptomic surveys and comparative genomic analyses, we aim to obtain new insights into molecular mechanisms of the adaptation to living at high salt in the saltern

2017-09-26 | GSE104102 | GEO

Six diploid strains grown in four conditions

Project description:Six strains of Saccharomyces cerevisiae were grown in four different environments representing a continuum of rich and poor natural conditions Keywords: Stress response, genetic diversity

2006-01-01 | GSE3021 | GEO

Targeted microarray analysis of three symbiotic cyanobacterial diazotroph strains in the South China Sea

Project description:We designed a new specific mRNA microarray targeting a subset of genes (748) of the diazotrophs Richelia intracellularis and Calothrix rhizosoleniae (genomes RintRC01, RintHH01, RintHM01 and CalSC01) which associate with diatom hosts. The aim was to be able to describe the gene expressions of genes related to several metabolic pathways and how they possibly differed between the closely related strains based on environment and host association. To better understand how the different environments might affect gene expressions, the samples were taken in depth profiles, at night and day, during a cruise in the South China Sea.

2019-10-31 | GSE139588 | GEO

Project description:Mutational fitness effects under changing environments

| PRJNA751388 | ENA

Study of microbial functional structure in Xiangjiang River sediment

Project description:Xiangjiang River (Hunan, China) has been contaminated with heavy metal for several decades by surrounding factories. However, little is known about the influence of a gradient of heavy metal contamination on the diversity, structure of microbial functional gene in sediment. To deeply understand the impact of heavy metal contamination on microbial community, a comprehensive functional gene array (GeoChip 5.0) has been used to study the functional genes structure, composition, diversity and metabolic potential of microbial community from three heavy metal polluted sites of Xiangjiang River. Three groups of samples, A, B and C. Every group has 3 replicates.

2016-08-02 | E-GEOD-85064 | biostudies-arrayexpress

A chromatin immunoprecipitation database for prokarytic organisms [Staphylococcus aureus]

Project description:Bacterial transcription factors (TFs) regulate gene expression to adapt to changing environments; when combined, the TF’s regulatory actions comprise transcriptional regulatory networks (TRNs). The chromatin immunoprecipitation (ChIP) assay is the major contemporary method for mapping in vivo protein-DNA interactions in the genome. It enables the genome-wide study of transcription factor binding sites (TFBSs) and gene regulation. Here, we present the genome-wide binding for major TFs in Staphylococcus aureus USA300 strains.

2021-08-15 | GSE182080 | GEO

Multiomic Profiling of the Liver Across Diets and Age in a Diverse Mouse Population

Project description:We profiled the liver transcriptome, proteome, and metabolome from 347 individuals from 58 isogenic strains of the BXD mouse population across age (7 to 24 months) and diet (low or high fat) to link molecular variations to metabolic traits. Several hundred genes are affected by diet and/or age at the transcript and protein levels. Orthologs of two aging-associated genes, St7 and Ctsd, were knocked down in C. elegans, reducing longevity in wildtype and mutant long-lived strains. The multiomics data were analyzed as segregating gene networks according to each independent variable, providing causal insight into segregating edges. Candidate hits were cross-examined in an independent Diversity Outbred mouse liver dataset segregating for similar diets, with ~80-90% of diet-related candidate genes found in common across datasets. Together, we have developed a large multiomics resource for multivariate analysis of complex traits and demonstrate a methodology for moving from observational associations to causal connections.

2025-11-22 | GSE310411 | GEO

Expression data from Aspergillus nidulans FGSCA26 and SirAdelta grown for 24,48, and 72h

Project description:The sirA gene encodes a member of sirtuin protein that is NAD(+)-dependent histone deacetylase (HDAC) and ubiquitous in eukaryote. DNA microarray analyses for Aspergillus nidulans FGSCA26 (WT) strain and Gene disruptant of sirA (SirAd) indicated that genes for synthesizing secondary metabolic products such as sterigmatocystin, penicillin G, emericellamide, aspernidine A, xanthone, austinol, and siderophores are down-regulated by SirA. Aspergillus nidulans WT and SirAd strains were cultured in 200 ml of GMM at 30Â°C for 24, 48, and 72 h, and their total RNA was purified as described above.

2016-08-09 | E-GEOD-85319 | biostudies-arrayexpress

Saccharomyces cerevisiae

Project description:Antagonistic pleiotropy conceals molecular adaptations in changing environments

| PRJNA597653 | ENA