Proteomics

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Cardiomyocyte-specific deletion of PTP1B protects against obesity-induced cardiomyopathy by regulating cardiac metabolic signaling


ABSTRACT: Cardiomyocyte-specific PTP1B KO mice are protected from high fat diet-induced cardiomyopathy. Whole tissue lysates from hearts of these mice were reduced, alkylated, trypsin digested, and phospho-enriched using Thermo Fisher's Fe NTA High Select columns. Results were generated using ProteomeDiscoverer2.5

INSTRUMENT(S): Orbitrap Eclipse

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

SUBMITTER: Jonathan Kirk  

PROVIDER: MSV000097436 | MassIVE | Mon Mar 24 15:51:00 GMT 2025

REPOSITORIES: MassIVE

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