Proteomics

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A multi-organ aging metabolomics model of a pro-drug activation deficiency murine model


ABSTRACT: Wild type and creatine kinase knock-out mice were subjected to a multi-organ metabolomic and proteomics comparative analysis using a streamline sample preparation method which allowed both metabolite and proteomic analysis of each organ. The metabolites were spiked with an heavy internal reference metabolite standards and analyzed using optimized reverse phase HPLC analysis in both positive and negative mode on a Q Exactive Classic. A reference standard library consisting of over 600 reference metabolite standards were analyzed on this system for extra confidence in the identification and quantification of this library of key metabolites. This repository solely contains the metabolomic data. A second repository will contain the matched proteomic data.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

SUBMITTER: Ben Orsburn  

PROVIDER: MSV000097802 | MassIVE | Mon May 05 08:29:00 BST 2025

REPOSITORIES: MassIVE

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