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Markers of neutrophil degranulation in the lung microenvironment linked to idiopathic pulmonary fibrosis severity and survival

ABSTRACT: Idiopathic pulmonary fibrosis (IPF) leads to progressive loss of lung function and mortality. Understanding mechanisms and markers of lung injury in IPF is paramount to improving outcomes for these patients. Despite the lack of systemic involvement in IPF, many analyses focus on identifying circulating prognostic markers. Using a proteomic discovery method followed by ELISA confirmation in multiple cohorts we explored novel markers of IPF survival in bronchoalveolar lavage fluid (BALF)

INSTRUMENT(S): Orbitrap Ascend

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Scott Matson

PROVIDER: MSV000098032 | MassIVE | Thu May 29 07:20:00 BST 2025

SECONDARY ACCESSION(S): PXD064413

REPOSITORIES: MassIVE

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