Proteomics

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IP-MS of SMARCC1-bound SWI/SNF complexes in PRT3789-treated Calu-6 and NCI-H1693 cell lines


ABSTRACT: Immunoprecipitation-mass spectrometry (IP-MS) was performed in Calu-6 (SMARCA4-WT) and NCI-H1693 (SMARCA4-del) cell lines treated with the SMARCA2-selective degrader PRT3789 for 6 or 48 hours. SWI/SNF complexes were immunoprecipitated using an antibody against SMARCC1 and analyzed by LC-MS/MS.

INSTRUMENT(S): Thermo Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Michael Hulse  

PROVIDER: MSV000098173 | MassIVE | Thu Jun 12 11:51:00 BST 2025

SECONDARY ACCESSION(S): PXD064953

REPOSITORIES: MassIVE

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