Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Metabolites from methylobacterium aquaticum

ABSTRACT: This dataset contains mass spectrometry data from a metabolomics experiment focused on metabolites from a lanthanide-utilizing bacteria known as methylobacterium aquaticum. Lanthanides are used in alcohol dehydrogenation for this species. From the 2025/07/02 run.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Methylobacterium Aquaticum (ncbitaxon:270351)

SUBMITTER: Allegra Aron

PROVIDER: MSV000098478 | MassIVE | Thu Jul 10 16:16:00 BST 2025

REPOSITORIES: MassIVE

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Metabolites from methylobacterium aquaticum

Project description:This dataset contains mass spectrometry data from a metabolomics experiment focused on metabolites from a lanthanide-utilizing bacteria known as methylobacterium aquaticum. Lanthanides are used in alcohol dehydrogenation for this species. This run infused metals just prior to ionization to ideally more easily observe potential adducts. From the 2025/07/15 run.

2025-07-22 | MSV000098595 | MassIVE

Metabolites from methylobacterium aquaticum

Project description:This dataset contains mass spectrometry data from a metabolomics experiment focused on metabolites from a iron and lanthanide-utilizing bacteria known as methylobacterium aquaticum. Lanthanides are used in alcohol dehydrogenation for this species.

2025-07-10 | MSV000098477 | MassIVE

GNPS_Metabolites from methylobacterium aquaticum

2025-03-24 | MSV000097429 | GNPS

Engineered Methylobacterium methanol

Project description:Engineered Methylobacterium methanol batch exponential

2014-12-22 | GSE34662 | GEO

Engineered Methylobacterium methanol

Project description:Engineered Methylobacterium methanol batch exponential strain CM702 vs. strain CM502

2014-12-22 | E-GEOD-34662 | biostudies-arrayexpress

Methylobacterium extorquens AM1 on acetate

Project description:Methylobacterium extorquens AM1 on acetate

2012-02-28 | PRD000445 | Pride

Methylobacterium extorquens AM1 on methanol

Project description:Methylobacterium extorquens AM1 on methanol

2012-02-28 | PRD000446 | Pride

Formaldehyde stress response in Methylobacterium extorquens AM1

Project description:The goal of this study was to use microarrays to identify genes differentially regulated under conditions of formaldehyde stress relative to two other stress conditions (oxidative, osmotic) in an effort to identify genes that might be involved in a formaldehyde-specific stress response, rather than a general stress response, in the model methylotroph Methylobacterium extorquens AM1.

2015-01-01 | GSE15631 | GEO

Transition from succinate to methanol growth in Methylobacterium Extorquens AM1

Project description:In order to provide information about the gene expression response that occurs when cells experience a change in carbon source, succinate limited chemostat cultures of Methylobacterium extorquens AM1 were grown to and maintained at an OD of ~0.63, transferred to flasks and methanol was added. Cells were harvested for RNA extraction at time: 0 min, 10 min, 30 min, 1 hr, 2 hr, 4 hr and 6 hr post transition. At 30 min, a no methanol addition sample was extracted as a carbon starvation control. These data were used in conjunction with flux, enzymatic and metabolite measurements to assess the changes in central metabolism during this transition. Abstract from manuscript: When organisms experience environmental change, how does their metabolic network reset and adapt to the new condition? This study focused on the mechanisms of metabolic adaptation occurring during the transition from succinate to methanol growth by the methylotrophic bacterium Methylobacterium extorquens, analyzing changes in carbon flux, gene expression, metabolites and enzymatic activities over time. Initially, cells experienced metabolic imbalance with excretion of metabolites, changes in nucleotide levels and cessation of cell growth. Though assimilatory pathways were induced rapidly, a transient block in carbon flow to biomass synthesis occurred, and enzymatic assays suggested methylenetetrahydrofolate dehydrogenase as one control point. This “downstream priming” mechanism ensures that significant carbon flux through these pathways does not occur until they are fully induced, precluding the buildup of toxic intermediates. Most metabolites that are required for growth on both carbon sources did not change significantly, even though transcripts and enzymatic activities required for their production changed radically, underscoring the concept of metabolic setpoints.

2011-08-01 | GSE22031 | GEO