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Neurons Sequester the Cholesterol-Inhibiting TFEB in Oligodendrocyte Cytoplasm to Safeguard Myelination and Neural Function

ABSTRACT: Samples ECL1_1260429_F1-F8 are TMT6plex samples fractionated into 8 fractions using the Pierce High pH Reversed-Phase Peptide Fractionation Kit. Samples are optic nerves protein lysates. Channels 126, 127, 128 are control samples (TFEBdPM-Halo) and channels 129, 130, 131 are mutant samples (Mog-Cre; TFEBdPM-Halo). Samples 1251765_F1-F8 are TMT6plex samples fractionated into 8 fractions using the Pierce High pH Reversed-Phase Peptide Fractionation Kit. Samples are day 14 in vitro differentiated oligodendrocytes protein lysates. Channels 126, 127, 128 are control samples (TFEBdPM-Halo) and channels 129, 130, 131 are mutant samples (Mog-Cre; TFEBdPM-Halo).

INSTRUMENT(S): Orbitrap Eclipse

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

SUBMITTER: Lu Sun

PROVIDER: MSV000098661 | MassIVE | Mon Jul 28 12:32:00 BST 2025

REPOSITORIES: MassIVE

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