Proteomics

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Exhaled breath from conventional and conventionalized mice


ABSTRACT: This is GCxGC MS data from exhaled breath from conventional and conventionalized mice as well as germ-free controls. Raw files in CDF format (Figure 2A-F, Figure S3A-B from our publication)

INSTRUMENT(S): SepSolve GCxGC-BenchTOF

ORGANISM(S): Gnotobiotic Mice

SUBMITTER: Audrey Odom John   Andrew L. Kau  

PROVIDER: MSV000098688 | MassIVE | Wed Jul 30 10:23:00 BST 2025

REPOSITORIES: MassIVE

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Publications


The gut microbiota is crucial to health, yet implementation of microbiota-based therapeutics is limited by the lack of rapid diagnostics. We hypothesize that breath contains gut microbe-derived volatile organic compounds (VOCs) reflecting microbiota composition and metabolism. In healthy children, we found that breath VOC composition (or volatilome), assessed by gas chromatography-mass spectrometry, correlates with gut microbiome composition and function. By capturing exhaled breath from human-s  ...[more]

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