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Differential Metabolomic Signatures in Plasma and Urine Under Mild and Moderate Hypothermia During Cardiopulmonary Bypass

ABSTRACT: Untargeted metabolomic profiling of plasma and urine samples from patients undergoing cardiopulmonary bypass (CPB) under mild or moderate hypothermia. Samples were collected at three time points: preoperative (T0), intraoperative (T1), and postoperative (T2). Both plasma and urine were analyzed using GC_MS and LC_qTOF_MS platforms. Plasma and Urine samples were extracted using cold methanol (9:1, v/v), and urine samples were pretreated with urease prior to extraction.

INSTRUMENT(S): GC-MS, LC-qTOF-MS

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Oguzhan Durmaz

PROVIDER: MSV000098691 | MassIVE | Wed Jul 30 13:19:00 BST 2025

REPOSITORIES: MassIVE

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