Proteomics

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The exhaled breath of monocolonized mice

ABSTRACT: This is GCxGC MS raw data from exhaled breath from colonized gnotobiotic mice with one of five common gut commensals including A. muciniphila, B. thetaiotaomicron, Collinsella aerofaciens, E. coli, and Ruminococcus torques and sterile media controls. Raw files in CDF format. (Fig 4B, Fig 5 from associated publication)

INSTRUMENT(S): SepSolve GCxGC-BenchTOF

ORGANISM(S): Escherichia Coli (ncbitaxon:562) Gnotobiotic Mice Bacteroides Thetaiotaomicron (ncbitaxon:818) Collinsella Aerofaciens (ncbitaxon:74426) Akkermansia Muciniphila (ncbitaxon:239935) [ruminococcus] Torques (ncbitaxon:33039)

SUBMITTER: Audrey Odom John   Andrew L. Kau  

PROVIDER: MSV000098692 | MassIVE | Wed Jul 30 14:02:00 BST 2025

REPOSITORIES: MassIVE

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Publications

The gut microbiota is crucial to health, yet implementation of microbiota-based therapeutics is limited by the lack of rapid diagnostics. We hypothesize that breath contains gut microbe-derived volatile organic compounds (VOCs) reflecting microbiota composition and metabolism. In healthy children, we found that breath VOC composition (or volatilome), assessed by gas chromatography-mass spectrometry, correlates with gut microbiome composition and function. By capturing exhaled breath from human-s  ...[more]

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