Proteomics

Dataset Information

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Metabolites from anaerobic culture headspace


ABSTRACT: This is GCxGC MS data from headspace VOCs from A. muciniphila, B. thetaiotaomicron, Collinsella aerofaciens, E. coli, and Ruminococcus torques and sterile media controls. Raw files in CDF format. (Fig 4A , Fig 5, Fig 3B from associated publication)

INSTRUMENT(S): SepSolve GCxGC-BenchTOF

ORGANISM(S): Escherichia Coli (ncbitaxon:562) Bacteroides Thetaiotaomicron (ncbitaxon:818) Collinsella Aerofaciens (ncbitaxon:74426) Akkermansia Muciniphila (ncbitaxon:239935) [ruminococcus] Torques (ncbitaxon:33039)

SUBMITTER: Audrey Odom John   Andrew L. Kau  

PROVIDER: MSV000098693 | MassIVE | Wed Jul 30 14:20:00 BST 2025

REPOSITORIES: MassIVE

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Publications


The gut microbiota is crucial to health, yet implementation of microbiota-based therapeutics is limited by the lack of rapid diagnostics. We hypothesize that breath contains gut microbe-derived volatile organic compounds (VOCs) reflecting microbiota composition and metabolism. In healthy children, we found that breath VOC composition (or volatilome), assessed by gas chromatography-mass spectrometry, correlates with gut microbiome composition and function. By capturing exhaled breath from human-s  ...[more]

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