Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Metabolomics data for Fumarate Hydratase deficiency triggers disulfidptosis under glucose deprivation

ABSTRACT: This dataset contains metabolomics and metabolic flux data related to the article "Fumarate Hydratase deficiency triggers disulfidptosis under glucose deprivation".

INSTRUMENT(S): Agilent 1290-LC/6546 QTOF MS

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Guowang Xu

PROVIDER: MSV000098754 | MassIVE | Wed Aug 06 23:33:00 BST 2025

REPOSITORIES: MassIVE

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Anaerobic growth in M9 + glucose + fumarate

Project description:Responses of Escherichia coli MG1655 as they grow anaerobically in M9 + glucose + fumarate (as electron acceptor) vs Aerobic growth OD 0.4 Keywords: time course

2006-03-08 | GSE4376 | GEO

Anaerobic growth in M9 + glucose + fumarate,genomic DNA reference

Project description:Responses of Escherichia coli MG1655 as they grow anaerobically in M9 + glucose + fumarate Keywords: time course

2006-03-08 | GSE4374 | GEO

Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells

Project description:Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells

| PRJNA556857 | ENA

Transcriptome of aerobically/anaerobically grown Actinobacillus succinogenes strain 130Z on fumarate/glucose

Project description:Transcriptome of aerobically/anaerobically grown Actinobacillus succinogenes strain 130Z on fumarate/glucose

2016-12-22 | GSE92722 | GEO

Glucose deprivation induced gene expression

Project description:Glucose deprivation induced gene expression

| PRJNA668528 | ENA

Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells

Project description:Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells

| PRJNA753846 | ENA

Function of YAP in glucose deprivation-induced gene expression

Project description:Knockdown of YAP in HCT116 cells by lentivirus-mediated shRNA, and after glucose deprivation treatment using total RNA for sequencing analysis to evaluate the function of YAP in glucose deprivation induced gene expression.

2023-11-29 | GSE215815 | GEO

Role of 4EBP1/2 in the response to glucose deprivation

Project description:We investigated the function of the mTORC1 substrates and mRNA translation regulators 4EBP1/2 in the response to glucose deprivation. We uncovered that targeting 4EBP1/2 expression had a direct impact on the survival rates of cells challenged with glucose deprivation. To further define the mechanisms underlying 4EBP1/2 function under glucose deprivation, we conducted a proteomics analysis of HEK293 shRNA control and HEK293 shRNA 4EBP1/2 grown in basal media or under glucose deprivation (1 mM glucose containing media) for 30 hours.

2024-03-28 | PXD040931 | Pride

Single six hours sleep deprivation causes glucose intolerance and hepatic steatosis.

Project description:To assess the effect of sleep deprivation on glucose metabolism and elucidate the mechanism, we established the mouse model wth C57BL/6J that is useful for the intervention on sleep deprivation associated diabetes and evaluate the liver metabolism and gene expression. Single six hours sleep deprivation induced increased hepatic glucose production assessed by pyruvate tolerance test and the hepatic triglyceride content was significantly higher in the sleep deprivation group than freely sleeping control group. Liver metabolites such as ketone bodies were increased in sleep deprivation group. Some gene expressions which associated with lipogenesis were increased.

2016-12-27 | GSE92913 | GEO

Transcriptional profiling of glucose deprivation resistant and glucose deprivation sensitive clones derived from IGROV-1 and SKOV3 ovarian cancer models and cultivated under either normal-glucose or low-glucose condition

Project description:This microarray experiment was designed to identify genes and pathways modulated in glucose deprivation resistant (GDR) and glucose deprivation sensitive (GDS) clones of ovarian cancer xenografts. Tumors were established in NOD/SCID mice by s.c. injection of human ovarian cancer cells (IGROV-1 and SKOV3). After sacrifice GDR and GDS clones were obtained from ex vivo cultures of tumors. Once isolated, GDR and GDS clones were cultivated in normal-glucose (0h) or low-glucose condition (6 h and 24 h). Two different time points were selected to investigate both early (6 h) and late (24 h) transcriptional effects of glucose deprivation in IGROV-1 and SKOV3-derived clones. Total RNA was extracted from samples and hybridized on Affymetrix GeneChip™ PrimeView™ Human Gene Expression Arrays. Based on assessment of RNA quality and on quality control analyses (including MAplots and boxplots), only one sample, corresponding to GDR condition at 6 h of glucose deprivation in SKOV3 model, was excluded because it was deemed not suitable for data analysis. In order to evaluate the effects of glucose deprivation in the two models, expression data of IGROV-1 and SKOV3-derived GDR and GDS clones were normalized and analyzed separately. Raw microarray data and pre-processed data matrices are available together with the applied protocols. Results of differential expression analysis are provided as supplementary tables of the associated publication.

2023-05-31 | E-MTAB-12150 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data