MS sequencing of GFAP fragments from TBI patients CSF
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ABSTRACT: Protein Glial fibrillary acidic protein, GFAP fragment identification (breakdown products, BDPs) and their label free peptide/ion quantification of GFAP immunoprecipitated from TBI patient's cerebrospinal fluid using a polyclonal anti-GFAP antibody. GFAP fragments of distinct molecular weights were cut out and in gel-digested prior to LC-MS/MS using Proteome discoverer 1.4. Peptide results from PD output files were combined from four TBI patients, 6 CSF samples to generate a multiconsensus peptide coverage map for each molecular weight fragment. See Wanner et al., BioRXiv 2025: https://doi.org/10.1101/2025.08.01.668181.
INSTRUMENT(S): Q Exactive Plus
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER:
Yu Chen
Wanner, Ina-Beate
PROVIDER: MSV000099415 | MassIVE | Tue Oct 07 15:43:00 BST 2025
REPOSITORIES: MassIVE
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