Proteomics

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Supporting MS data for paper (doi:10.1038/s41565-025-02080-2) by Goerzen, D. et al (2025), titled "Machine perception liquid biopsy identifies brain tumours via systemic immune and tumour microenvironment signature"


ABSTRACT: Supporting MS data for paper (doi:10.1038/s41565-025-02080-2) by Goerzen, D. et al (2025), titled "Machine perception liquid biopsy identifies brain tumors via systemic immune and tumor microenvironment signature." The index of experiments, related MS files, and labels is provided in the uploaded Excel file.

INSTRUMENT(S): Orbitrap Eclipse

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Alban Ordureau  

PROVIDER: MSV000099468 | MassIVE | Mon Oct 13 10:27:00 BST 2025

REPOSITORIES: MassIVE

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Publications


The detection and identification of intracranial tumours is limited by the lack of accurate biomarkers and requires invasive biopsy procedures. We investigated a machine perception liquid biopsy approach to detect and identify intracranial tumours from peripheral blood and to discover biomarkers responsible for the predictions. Quantum well defect-modified single-walled carbon nanotubes stabilized with single-stranded DNA, interrogating 739 plasma samples from brain tumour patients, were used to  ...[more]

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